Set Your Location to See Relevant Information

Setting your location helps us to show you nearby providers and locations based on your healthcare needs.

A Multicenter, Randomized, Double-blind, Chronic-dosing, Parallel-group, Placebo-controlled Phase 3 Study To Evaluate The Efficacy And Safety Of Benralizumab 100 Mg In Patients With Moderate To Very Severe Chronic Obstructive Pulmonary Disease (COPD) With A History Of Frequent COPD Exacerbations And Elevated Peripheral Blood Eosinophils (RESOLUTE) (PROTOCOL # D3251C00014)

Study Details
Brief Summary:

Phase 3 study to evaluate the efficacy and safety of a benralizumab in patients with moderate to very severe COPD with a history of frequent COPD exacerbations and elevated peripheral blood eosinophils (≥300/μL).

Eligible patients must have a history of ≥2 moderate and/or severe COPD exacerbations in the previous year despite receiving triple (ICS/LABA/LAMA) background therapy. Eligible patients must also have an elevated blood eosinophil count.

The treatment period will be of variable duration and will continue until the last patient has the opportunity to complete a minimum of 56 weeks, at which point all patients will complete the study. The primary endpoint will be analyzed at Week 56.

Learn More NCT number
Principal Investigator(s)
Paul Sachs, MD
Carolina Garavito at 203-358-8879


  • SHMG- Pulmonary Associates
    29 Hospital Plaza
    Stamford, CT 06902

Our website uses cookies

This website uses cookies to give you the very best experience. Your continued use of this site is considered permission by you to use cookies in this manner. Please review our Privacy Policy and Terms of Use for more information about the data we collect and the types of cookies we use. Please note, if you link off our website to a 3rd party site of any kind, that website has its own terms and conditions.