A Randomized Phase II Trial of Adjuvant Trastuzumab Emtansine (T-DM1) Followed by Subcutaneous Trastuzumab versus Paclitaxel in

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A Randomized Phase II Trial of Adjuvant Trastuzumab Emtansine (T-DM1) Followed by Subcutaneous Trastuzumab versus Paclitaxel in Combination with Subcutaneous Trastuzumab for Stage 1 HER2-positive Breast Cancer - ATEMPT 2.0 (DF/HCC 21-159)

Study Details

This research study is studying how well newly diagnosed breast cancer that has tested positive for a protein called HER2 responds using one of two different combination of HER2-directed therapies as a treatment after surgery.

The name of the study drugs involved are:

  • Trastuzumab-emtansine (T-DM1, Kadcyla)
  • Trastuzumab SC (Herceptin Hylecta)
  • Paclitaxel

Learn More

ClinicalTrials.gov NCT number
NCT04893109

Principal Investigators

  • Steve Lo, MD
Sponsor(s)
Dana-Farber Cancer Institute
Contact
Mary Miller, LPN at 203-358-8879
or officeofresearch@stamhealth.org

Location

  • Bennett Cancer Center
    One Hospital Plaza
    Stamford, CT 06902
    Main: 203-276-2695

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