A single arm phase II study of ADjuvant Endocrine therapy, Pertuzumab, and Trastuzumab for patients with anatomic stage I hormone receptor-positive, HER2-positive breast cancer

A single arm phase II study of Adjuvant Endocrine therapy, subcutaneous Pertuzumab and Trastuzumab fixed-dose combination for patients with anatomic stage I hormone receptor-positive, HER2-positive breast cancer (ADEPT) (DF/HCC 20-347)

This research study is studying a combination of HER2-directed therapies (trastuzumab and pertuzumab) and hormonal therapy as a treatment after surgery for hormone receptor positive breast cancer.

The study drugs involved in this study are:

  • A combination of trastuzumab and pertuzumab given as an injection under the skin (PHESGO)
  • Hormonal (endocrine) Treatment

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Principal Investigator(s)

Steve Lo, MD

Sponsor(s)

Dana-Farber Cancer Institute

Location

Bennett Cancer Center
One Hospital Plaza
Stamford, CT 06902
Main: 203-358-8879

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